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Lubricin Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA3118

Catalog No. PA3118


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Description

Description

PA3-118 detects Lubricin in human samples. PA3-118 has been successfully used in Western blot procedures. By Western blot, this antibody detects a 280 kDa protein representing recombit human Lubricin. PA3-118 works best on purified or recombit samples under non-reducing conditions. PA3-118 immunogen is a synthetic peptide corresponding to residues C L(1356) P N I R K Q P D G Y D Y Y A F S K D Q(1374) of human Lubricin. This polyclonal antibody has been referred to as: JSCLPN.

Lubricin is a glycoprotein encoded by the PRG4 gene. It has been identified as a component of joint lubrication and synovial homeostasis by reducing friction in joints and preventing synovial cell overgrowth. It is a large, water soluble molecule that acts as a carrier for insoluble surface-active phospholipid (SAPL). Depletion of lubricin function has been associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), an arthritic-like autosomal recessive disorder.
Specifications

Specifications

Lubricin
Polyclonal
Unconjugated
PRG4
Liquid
PRG4
Synthetic peptide corresponding to residues C L(1356) P N I R K Q P D G Y D Y Y A F S K D Q(1374) of human Lubricin.
Affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide
Q92954
Megakaryocyte stimulating factor, superficial zone proteoglycan, Proteoglycan-4 (PRG4).
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
10216
Documents
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