Lubricin Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA3118
PA3-118 detects Lubricin in human samples. PA3-118 has been successfully used in Western blot procedures. By Western blot, this antibody detects a 280 kDa protein representing recombit human Lubricin. PA3-118 works best on purified or recombit samples under non-reducing conditions. PA3-118 immunogen is a synthetic peptide corresponding to residues C L(1356) P N I R K Q P D G Y D Y Y A F S K D Q(1374) of human Lubricin. This polyclonal antibody has been referred to as: JSCLPN.Lubricin is a glycoprotein encoded by the PRG4 gene. It has been identified as a component of joint lubrication and synovial homeostasis by reducing friction in joints and preventing synovial cell overgrowth. It is a large, water soluble molecule that acts as a carrier for insoluble surface-active phospholipid (SAPL). Depletion of lubricin function has been associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), an arthritic-like autosomal recessive disorder.
|Synthetic peptide corresponding to residues C L(1356) P N I R K Q P D G Y D Y Y A F S K D Q(1374) of human Lubricin.|
|PBS with 1mg/mL BSA and 0.05% sodium azide|
|Megakaryocyte stimulating factor, superficial zone proteoglycan, Proteoglycan-4 (PRG4).|
|-20° C, Avoid Freeze/Thaw Cycles|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok