LXR alpha, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA1332
Liver X receptors (LXRs), also known as RLD1, are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs form heterodimeric complexes with the retinoic acid receptors (RARs) once activated by their respective oxysterol ligands. Two known isoforms, alpha and beta, are differentially expressed; the alpha isoform predominantly expressed in liver, whereas beta isoform expression has been shown to be ubiquitous.The corresponding gene for the LXR alpha is NR1H3.PA1-332 detects LXR alpha in mouse samples. PA1-332 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~50kDa protein representing LXR alpha in mouse liver samples.The PA1-332 immunogen is a synthetic peptide corresponding to residues T(35) C I L R E E A R M P Q S T G(49) of mouse LXR alpha. The PA1-332 immunizing peptide (Cat. # PEP-272) is available for use in neutralization and control experiments.
|Synthetic peptide corresponding to residues T(35) C I L R E E A R M P Q S T G(49) of mouse LXR alpha.|
|Antigen affinity chromatography|
|PBS with 1mg/mL BSA and 0.05% sodium azide|
|Liver X Receptor Alpha, Oxysterols receptor LXR-alpha, Liver X receptor alpha, Nuclear orphan receptor LXR-alpha|
|-20° C, Avoid Freeze/Thaw Cycles, Avoid Freeze/Thaw Cycles|
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