LXR beta Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA1333
PA1-333 detects LXR beta in human, rat and mouse samples. PA1-333 has been successfully used in Western blot and IF procedures. By Western blot, this antibody detects an ~51 kDa protein representing LXR beta in rat and mouse liver samples. The PA1-333 immunogen is a synthetic peptide corresponding to residues R(113) Y A C R G S G T C Q M D A(126) of rat LXR beta. The PA1-333 immunizing peptide (Cat. No. PEP-271) is available for use in neutralization and control experiments.Liver X receptors (LXRs), also known as RLD1, are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs form heterodimeric complexes with the retinoic acid receptors (RARs) once activated by their respective oxysterol ligands. Two known isoforms, alpha and beta, are differentially expressed; the alpha isoform predomitly expressed in liver, whereas beta isoform expression has been shown to be ubiquitous. The corresponding gene for the LXR beta is NR1H2.
|Synthetic peptide corresponding to residues R(113) Y A C R G S G T C Q M D A(126) of rat LXR beta.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 1mg/mL BSA and 0.05% sodium azide|
|P55055, Q60644, Q62755|
|Nr1h2, Liver X Receptor Beta, Oxysterols receptor LXR-beta, Nuclear orphan receptor LXR-beta, Ubiquitously-expressed nuclear receptor, Nuclear recepto|
|-20° C, Avoid Freeze/Thaw Cycles|
|22260, 58851, 7376|
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