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MD-1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112813

Catalog No. 01-675-805


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Description

Description

Toll-like receptors (TLRs) are evolutionarily conserved patternrecognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway.. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD -1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.
Specifications

Specifications

MD-1
Polyclonal
PBS with 0.02% sodium azide
O95711, O88188
MD-1
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
17084, 291359, 9450
Western Blot
Unconjugated
LY86
Liquid
LY86
Synthetic peptide corresponding to 15 residues from near the center of human MD-1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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