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Lyn Mouse, Unlabeled, Clone: 42, BD

Mouse Monoclonal Antibody

$232.00

Specifications

Antigen Lyn
Isotype IgG1
Immunogen Human Lyn aa. 1-138
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB610003
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BD Biosciences
610003
50μg
Each for $232.00
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BDB610004
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BD Biosciences
610004
150μg This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

Lyn is a 56 kDa cytosolic tyrosine kinase that belongs to the Src family of kinases. In addition to Src, this family includes lck, Fgr, Hck, Blk, Yes, fyn, and Yrk kinases. The lyn gene was isolated from a human placenta cDNA library and later found in a variety of cell types. Similar to other members of the Src family of tyrosine kinases, Lyn has been implicated in the regulation of cell signaling mechanisms. Lyn's function has primarily been studied in hematopoietic cells where it is associated with the high-affinity IgE receptor in basophils. It also associates with p120 Ras-GAP in thrombin-stimulated platelets. This association corresponds to an increase in Lyn kinase activity. Lyn is often observed as a doublet of about 56 kDa and 53 kDa. These forms may represent alternative splicing products of lyn mRNA.
Specifications

Specifications

Lyn
Human Lyn aa. 1-138
Unconjugated
Cell Biology
Mouse
Affinity Purified
Monoclonal
Store undiluted at -20°C.
IgG1
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
RUO
42
250μg/mL
SDS
Product Certifications

For Research Use Only.

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