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Lysozyme Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA140308

Catalog No. 01-676-427


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Description

Description

PA1-40308 detects Lysozyme from human samples. PA1-40308 has been successfully used in ELISA, immunoprecipitation, and Western blot applications. The PA1-40308 imunogen is human lysozyme.

Lysozymes is a 14 kd natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is an antimicrobial protein secreted by polymorphonuclear leukocytes and is widely distributed in secretions such as airway secretions and nasal fluid whereas it is the most effective antimicrobial protein. It is also produced by monocytes, macrophages and epithelial cells, and is one of the anti-microbial agents found in human milk, spleen, lung, kidney, white blood cells, plasma, aliva, and tears. Lysozyme is able to kill bacteria by enzymatic lysis of bacterial cell walls and by a nonenzymatic mechanism. Allthough lysozyme is highly active against many gram-positive bacteria it is ineffective against gram-negative bacteria unless potentiated by certain cofactors (lactoferrin, antibody-complement or hydrogen peroxide-ascorbic acid). Next to its antimicrobial activity lysozyme has many other physiological functions including inactivation of certain viruses, important roles in surveillance of membranes of mammalian cells, immune regulatory activity, anti-inflammatory and antitumor activity.
Specifications

Specifications

Lysozyme
Polyclonal
Unconjugated
LYZ
Liquid
LYZ
Human lysozyme.
Protein A
RUO
Antibody
Polyclonal
Human
ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
0.1 mg/mL
PBS with 0.1% BSA and 0.02% sodium azide
P61626
LYZ
Rabbit
IgG
100 μg
4° C
Primary
4069
Documents
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