LOXL2 Mouse anti-Human, Clone: 262418, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523963
Reconstitute at 0.5 mg/mL in sterile PBS.Lysyl Oxidase (LO) is an extracellular, copper-dependent enzyme that initiates the cross-linking of collagens and elastin by catalyzing the oxidative deamination of peptidyl lysine to alpha-aminoadipic-delta-semialdehyde. Members of LO family have diverse functions which include tumor suppression and cell adhesion and senescence. LOXL2, a 87KDa protein, is a novel member of this family. It contains 3 potential N-linked glycosylation sites, 4 scavenger receptor cysteine-rich (SRCR) domains and highly conserved copper-binding and Lysyl-tyrosylquinone cofactor sites. It is a component of extracellular matrix that might be involved in cell adhesion and senescence. Role of LOXL2 has been implicated in maligt transformation.
|PBS with 5% trehalose and No Preservative|
|LOXL2, Lysyl oxidase-like protein 2, Lysyl oxidase related 2, Lysyl oxidase-like 2, WS9-14, LOR2, Lysyl oxidase homolog 2|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunoprecipitation, Western Blot|
|Mouse myeloma cell line NS0-derived recombit human Lysyl Oxidase Homolog 2/LOXL2 Gln26-Gln744 (predicted)|
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