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LOX Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA146020

Catalog No. PA146020


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Description

Description

Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extra cellular matrix. As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.
Specifications

Specifications

LOX
Polyclonal
whole serum with 0.1% sodium azide
P28300, P28301, P16636
LOX , lysyl oxidase , MGC105112 , protein-lysine 6-oxidase
Rabbit
IgG
RUO
Antibody
Polyclonal
Human, Mouse, Non-human primate, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Unconjugated
LOX
Liquid
LOX
Two synthetic peptides (residues 150-200 and 275-325) of the rat LOX protein.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
16948, 24914, 4015
Documents
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