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LZTR2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520903

Catalog No. PIPA520903


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Description

Description

A suggested positive control is mouse kidney tissue lysate. PA5-20903 can be used with blocking peptide PEP-1017.

LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.
Specifications

Specifications

LZTR2
Polyclonal
Unconjugated
SEC16B
Liquid
SEC16B
An 18 amino acid peptide near the carboxy terminus of human LZTR2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q96JE7, Q91XT4, Q75N33
LZTR2, PGPR-p117, RGPR, SEC16S; RGPR-p117; leucine zipper transcription regulator 2; protein SEC16 homolog B; protein transport protein Sec16B; regucalcin gene promoter region-related protein p117; regucalcin gene promotor region related protein
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
89866, 89867, 89868
Documents
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