LZTR2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520903
A suggested positive control is mouse kidney tissue lysate. PA5-20903 can be used with blocking peptide PEP-1017.LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.
|An 18 amino acid peptide near the carboxy terminus of human LZTR2.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Q96JE7, Q91XT4, Q75N33|
|LZTR2, PGPR-p117, RGPR, SEC16S; RGPR-p117; leucine zipper transcription regulator 2; protein SEC16 homolog B; protein transport protein Sec16B; regucalcin gene promoter region-related protein p117; regucalcin gene promotor region related protein|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|89866, 89867, 89868|
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