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MAGED1/MAGED2 Rabbit anti-Canine, Equine, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523347

Catalog No. PIPA523347


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Description

Description

MAGE-D2, also known as Melanoma-associated antigen D2, belongs to the melanoma antigen encoding gene (MAGE) family with a MAGE domain. Rat and mouse orthologues have been isolated. Compared to other proteins (MAGE-A, MAGE- B and MAGE-C clusters) MAGE-D2 is expressed ubiquitously. This intracellular protein shows high expression in specific brain regions and in the interstitium of testes. Though the exact function of this protein is yet to be deduced, MAGE-D2 is considered as a hot spot for X-linked mental retardation. Research reveals that MAGE-D2 might have some role in breast and gastric cancer, as well as in hepatocellular carcinoma. MAGE-D2 is also known to interact physically with p53 and modify its activity, thus acting as a p53-dissociator.
Specifications

Specifications

MAGED1/MAGED2
Polyclonal
Unconjugated
MAGED2
Liquid
LOC100147318, MAGED1, MAGED2
Synthetic peptide (CKVQKKDPKEWAAQYR & CEFVKQKYLDYARVPNSN) of MAGE-D1/2 protein.
Protein A
RUO
Antibody
Polyclonal
Canine, Equine, Human, Mouse, Non-human primate, Rat
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q9UNF1, Q9Y5V3, Q9QYH6, Q9ES73
Maged1, Maged2, PP2250, PRO2292, NRAGE, Melanoma-associated antigen D1, MAGE tumor antigen CCF, MAGE-D1 antigen, Neurotrophin receptor-interacting MAGE homolog, 11B6, Breast cancer-associated gene 1 protein, BCG-1, JCL-1, Melanoma-associated antigen D2
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100060545, 100147318, 10916, 113947, 480923, 80884, 84469, 94275, 9500
Documents
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