MAGED1/MAGED2 Rabbit anti-Canine, Equine, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523347
DescriptionMAGE-D2, also known as Melanoma-associated antigen D2, belongs to the melanoma antigen encoding gene (MAGE) family with a MAGE domain. Rat and mouse orthologues have been isolated. Compared to other proteins (MAGE-A, MAGE- B and MAGE-C clusters) MAGE-D2 is expressed ubiquitously. This intracellular protein shows high expression in specific brain regions and in the interstitium of testes. Though the exact function of this protein is yet to be deduced, MAGE-D2 is considered as a hot spot for X-linked mental retardation. Research reveals that MAGE-D2 might have some role in breast and gastric cancer, as well as in hepatocellular carcinoma. MAGE-D2 is also known to interact physically with p53 and modify its activity, thus acting as a p53-dissociator.
|LOC100147318, MAGED1, MAGED2|
|Synthetic peptide (CKVQKKDPKEWAAQYR & CEFVKQKYLDYARVPNSN) of MAGE-D1/2 protein.|
|Canine, Equine, Human, Mouse, Non-human primate, Rat|
|PBS with 0.05% BSA and 0.05% sodium azide|
|Q9UNF1, Q9Y5V3, Q9QYH6, Q9ES73|
|Maged1, Maged2, PP2250, PRO2292, NRAGE, Melanoma-associated antigen D1, MAGE tumor antigen CCF, MAGE-D1 antigen, Neurotrophin receptor-interacting MAGE homolog, 11B6, Breast cancer-associated gene 1 protein, BCG-1, JCL-1, Melanoma-associated antigen D2|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|100060545, 100147318, 10916, 113947, 480923, 80884, 84469, 94275, 9500|
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