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MAGED1 Mouse anti-Human, Clone: 353124, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524096

Catalog No. PIMA524096


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Description

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

MAGE-D2, also known as Melanoma-associated antigen D2, belongs to the melanoma antigen encoding gene (MAGE) family with a MAGE domain. Rat and mouse orthologues have been isolated. Compared to other proteins (MAGE-A, MAGE- B and MAGE-C clusters) MAGE-D2 is expressed ubiquitously. This intracellular protein shows high expression in specific brain regions and in the interstitium of testes. Though the exact function of this protein is yet to be deduced, MAGE-D2 is considered as a hot spot for X-linked mental retardation. Research reveals that MAGE-D2 might have some role in breast and gastric cancer, as well as in hepatocellular carcinoma. MAGE-D2 is also known to interact physically with p53 and modify its activity, thus acting as a p53-dissociator.
Specifications

Specifications

MAGED1
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q9Y5V3
Maged1, Maged2, PP2250, PRO2292, NRAGE, Melanoma-associated antigen D1, MAGE tumor antigen CCF, MAGE-D1 antigen, Neurotrophin receptor-interacting MAGE homolog, 11B6, Breast cancer-associated gene 1 protein, BCG-1, JCL-1, Melanoma-associated antigen D2
Mouse
IgG2B
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
9500
Flow Cytometry, Immunocytochemistry, Immunofluorescence
353124
Unconjugated
MAGED1
Lyophilized
MAGED1
E. coli-derived recombit human NRAGE Met1-Glu778
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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