MVP Rat anti-Human, Clone: LMR5, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA135590
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
|antibody with 1% BSA and 0.1% sodium azide|
|Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)|
|110 kDa LRP-protein (p110).|
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