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MAP1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA14271

Catalog No. PA14271


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Description

Description

PA1-4271 detects the MAP-1 (Modulator of Apoptosis) protein in human samples. PA1-4271 has been successfully used in Western blot procedures. This antibody detects a ~36 kDa protein representing human MAP-1 in 293T cells. PA1-4271 immunizing peptide corresponds to amino acid residues 337-351 of the human MAP-1 protein.

A novel Bax-associating protein, named MAP-1 (Modulator of Apoptosis), mediates caspase-dependent apoptosis in mammalian cells when overexpressed. MAP-1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-X(L) of the Bcl-2 family in vitro and in vivo in mammalian cells. These data suggest that MAP-1 mediates apoptosis through a mechanism that involves binding to Bax.
Specifications

Specifications

MAP1
Polyclonal
Unconjugated
MOAP1
Liquid
MOAP1
Synthetic peptide: E(337) E E A L L Q A I L E G N F T(351) of the human MAP-1 protein
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q96BY2
Paraneoplastic antigen MA4
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
64112
Documents
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