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MAP1B Mouse, Unlabeled, Clone: 6, BD

Mouse Monoclonal Antibody

$207.00 - $415.00

Specifications

Antigen MAP1B
Isotype IgG2a
Immunogen Mouse MAP1B aa. 1745-1858
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB612678
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BD Biosciences
612678
50μg
Each for $207.00
Add to cart
 
BDB612679
View Documents
BD Biosciences
612679
150μg
Each for $415.00
Add to cart
 
Description

Description

Microtubule-associated proteins (MAPs) play a crucial role in the development and structure of nerve cells. These proteins are important for the assembly and stability of microtubles during neurite outgrowth and for the morphology of neuronal processes, such as dendrites. MAP1B encodes for a single precursor protein that is cleaved to produce a single heavy chain of 280kDa and a light chain of 32kDa which become noncovalently associated. Expression levels of MAP1B are reportedly highest in the brain and are modulated during development as reported with gene silencing experiments that implicate MAP1B's role during neuronal differentiation. In addition, MAP1B can be selectively phosphorylated depending on the cell type, subcellular localization and developmental phase. In neurons, MAP1B is expressed as a glycoprotein at the plasma membrane, where it can interact with proteins participating in axonal guiding. MAP1B has been reported to be observable to migrate in a range between 320-340kDa.

Western Blotting

Specifications

Specifications

MAP1B
Mouse MAP1B aa. 1745-1858
Unconjugated
Cell Biology
Murine
Affinity Purified
Monoclonal
Store undiluted at -20°C.
IgG2a
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
6
250μg/mL
SDS

For Research Use Only.

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