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p38 MAPK alpha Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA514055

Catalog No. PIPA514055

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This antibody is predicted to react with rat and zebrafish based on sequence homology.

MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Specifications

Specifications

p38 MAPK alpha
Polyclonal
PBS with 0.09% sodium azide
Q16539, P47811
Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38alpha, MAP kinase p38alpha, Cytokine suppressive anti-inflammatory drug binding protein, CSAID binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1432, 26416
Immunohistochemistry, Western Blot
Unconjugated
MAPK14
Liquid
MAPK14
KLH conjugated synthetic peptide between 158-192 amino acids from human MAPK14
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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