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EB1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141270

Catalog No. 01-675-616


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Description

Description

EB1 family proteins are evolutionarily conserved proteins that bind microtubule plus-ends and centrosomes and regulate the dynamics and organization of microtubules. The MAPRE genes encode the EB1 family proteins. The human MAPRE genes MAPRE1, MAPRE2, and MAPRE3 code for EB1, RP1, and EBF3 proteins, respectively.  EB1 family members appear to be expressed ubiquitously. The EB1 (MAPRE1) gene, at 20q11.2, is fused to MLL in an adult patient with pro-B acute lymphoblastic leukemia.   EB1 is a microtubule-associated protein that interacts with the colorectal adenomatous polyposis coli tumor-suppressor protein and plays important roles in regulating microtubule dynamics, cell polarity, and chromosome stability.
Specifications

Specifications

EB1
Polyclonal
PBS with 0.2% gelatin and 0.05% sodium azide
Q15691
EB1, MGC117374, MGC129946
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
22919
Western Blot
Unconjugated
MAPRE1
Liquid
MAPRE1
Synthetic peptide corresponding to residues C(228) Q E N E G E N D P V L Q R I(242) of human MAPRE1.
Protein G
RUO
Antibody
Polyclonal
Human
Documents
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