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MARVELD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520853

Catalog No. PIPA520853


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Description

Description

A suggested positive control is mouse heart tissue lysate. PA5-20853 can be used with blocking peptide PEP-0967.

MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2’-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.
Specifications

Specifications

MARVELD1
Polyclonal
Unconjugated
MARVELD1
Liquid
MARVELD1
A 16 amino acid peptide from near the amino terminus of human MARVELD1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9BSK0, Q7TQJ1
GB14, MARVD1, MRVLDC1, RP11-548K23.8, bA548K23.8; MARVEL (membrane-associating) domain containing 1; MARVEL domain-containing protein 1; putative MARVEL domain-containing protein 1
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
277010, 309375, 83742
Documents
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