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ST14 Mouse anti-Human, Clone: 416802, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524154

Catalog No. PIMA524154


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Description

Description

This antibody detects human Matriptase/ST14 Catalytic Domain in direct ELISAs and Western blots. Reconstitute at 0.5 mg/mL in sterile PBS.

The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
Specifications

Specifications

ST14
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q9Y5Y6
HAI, MT-SP1, MTSP1, PRSS14, SNC19, TADG15, TMPRSS14, membrane-type serine protease 1, prostamin, serine protease 14, serine protease TADG-15, suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin), suppressor of tumorigenicity 14 protein, tumor associated differentially expressed gene 15 protein,
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
6768
Flow Cytometry, Western Blot
416802
Unconjugated
ST14
Lyophilized
ST14
E. coli-derived recombit human Matriptase/ST14 Catalytic Domain Val615-Val855
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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