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PCBP4 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520359

Catalog No. PIPA520359


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Description

Description

A suggested positive control is Hela cell lysate. PA5-20359 can be used with blocking peptide PEP-0479.

MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified.
Specifications

Specifications

PCBP4
Polyclonal
PBS with 0.02% sodium azide
P57723
CBP, LIP4, MCG10; LYST-interacting protein; RNA binding protein MCG10; alpha-CP4; poly(rC)-binding protein 4
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
57060
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
PCBP4
Liquid
PCBP4
A 17 amino acid peptide from near the carboxy terminus of human MCG10.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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