PCBP4 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520359
A suggested positive control is Hela cell lysate. PA5-20359 can be used with blocking peptide PEP-0479.MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified.
|PBS with 0.02% sodium azide|
|CBP, LIP4, MCG10; LYST-interacting protein; RNA binding protein MCG10; alpha-CP4; poly(rC)-binding protein 4|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|A 17 amino acid peptide from near the carboxy terminus of human MCG10.|
|Antigen affinity chromatography|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok