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MCL1 Rabbit anti-Human, Polyclonal, Invitrogen™

Catalog No. 01673659
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Catalog No. Quantity
01-673-659 1 mL
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Catalog No. 01-673-659 Supplier Thermo Scientific Supplier No. PA138096

Description

Rabbit Polyclonal Antibody

MCL1 belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is tonsil or small intestine tissue.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCL1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
Gene MCL1
Gene Accession No. Q07820
Gene Alias BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT, bcl-2-like protein 3, bcl-2-related protein EAT/mcl1, induced myeloid leukemia cell differentiation protein Mcl-1, myeloid cell leukemia ES
Gene Symbols MCL1
Host Species Rabbit
Immunogen Synthetic peptide derived from internal region of human MCL-1.
Purification Method Antigen affinity chromatography
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4170
Target Species Human
Content And Storage 4° C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG
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