MCL1 Rabbit anti-Human, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA138096
MCL1 belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is tonsil or small intestine tissue.
|PBS with 1% BSA and <0.1% sodium azide; pH 7.6|
|BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT, bcl-2-like protein 3, bcl-2-related protein EAT/mcl1, induced myeloid leukemia cell differentiation protein Mcl-1, myeloid cell leukemia ES|
|4° C, do not freeze|
|Synthetic peptide derived from internal region of human MCL-1.|
|Antigen affinity chromatography|
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