MCM3 Mouse anti-Human, Clone: 2H3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA519313
Peptide Sequence: AKDGDSYDPY DFSDTEEEMP QVHTPKTADS QETKESQKVE LSESRLKAFK VALLDVFREA HAQSIGMNRL TESINRDSEE PFSSVEIQAA LSKMQDDNQV MVSEGIIFLIThe protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
|PBS with no preservative; pH 7.4|
|RP1-108C2.3, HCC5, P1-MCM3, P1.h, RLFB, DNA polymerase alpha holoenzyme-associated protein P1, DNA replication factor MCM3, DNA replication licensing factor MCM3, MCM3 minichromosome maintece deficient 3, RLF subunit beta, cervical cancer proto-oncogene 5, hRlf beta subunit, minichromosome maintece deficient 3, p102, replication licensing factor, beta subunit|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Immunocytochemistry, Immunofluorescence, Western Blot|
|MCM3 (NP_002379, 699 a.a. ∽ 808 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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