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MCM3 Mouse anti-Human, Clone: 2H3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA519313

Catalog No. PIMA519313


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Description

Description

Peptide Sequence: AKDGDSYDPY DFSDTEEEMP QVHTPKTADS QETKESQKVE LSESRLKAFK VALLDVFREA HAQSIGMNRL TESINRDSEE PFSSVEIQAA LSKMQDDNQV MVSEGIIFLI

The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
Specifications

Specifications

MCM3
Monoclonal
0.49 mg/mL
PBS with no preservative; pH 7.4
P25205
RP1-108C2.3, HCC5, P1-MCM3, P1.h, RLFB, DNA polymerase alpha holoenzyme-associated protein P1, DNA replication factor MCM3, DNA replication licensing factor MCM3, MCM3 minichromosome maintece deficient 3, RLF subunit beta, cervical cancer proto-oncogene 5, hRlf beta subunit, minichromosome maintece deficient 3, p102, replication licensing factor, beta subunit
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
4172
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
2H3
Unconjugated
MCM3
Liquid
MCM3
MCM3 (NP_002379, 699 a.a. ∽ 808 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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