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MCM6, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA126584

Catalog No. PIPA126584

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

PA1-26584 detects MCM6 from human samples. PA1-26584 is expected to cross react with mouse and rat (both 97% conserved) due to sequence homology.PA1-26584 has been successfully used in Western blot procedures.The PA1-26584 immunogen is a synthetic peptide corresponding to a portion of human Minichromosome Maintenance Deficient 6 encoded by exon 17.
Specifications

Specifications

MCM6
Polyclonal
Unconjugated
MCM6
Purified
MCM6
Synthetic peptide corresponding to a portion of human Minichromosome Maintenance Deficient 6 encoded by exon 17.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Murine, Rat
Western Blot
1mg/mL
tris phosphate, tris citrate with 0.1% sodium azide; pH 7-8
Q14566, P97311, Q62724
MCG40308, Mis5, P105MCM
Goat
IgG
50μL
Store at 4°C
Primary
4175
Documents
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