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MCM6, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Supplier:  Thermo Scientific PA126584

Catalog No. PIPA126584

Item Discontinued This item has been discontinued by the supplier and is no longer available. Please reach out to your sales representative.


Description

Description

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

PA1-26584 detects MCM6 from human samples. PA1-26584 is expected to cross react with mouse and rat (both 97% conserved) due to sequence homology.PA1-26584 has been successfully used in Western blot procedures.The PA1-26584 immunogen is a synthetic peptide corresponding to a portion of human Minichromosome Maintenance Deficient 6 encoded by exon 17.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MCM6
Polyclonal
Unconjugated
Q14566, P97311, Q62724
MCM6
Synthetic peptide corresponding to a portion of human Minichromosome Maintenance Deficient 6 encoded by exon 17.
50 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Western Blot
1mg/mL
MCM6
MCG40308, Mis5, P105MCM
Goat
Antigen affinity chromatography
RUO
4175
Store at 4°C, do not freeze
Purified
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