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MCM7, Polyclonal, Invitrogen™

Catalog No. PIPA126585
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Quantity:
50 μL
Catalog No. Quantity
PIPA126585 50 μL
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Catalog No. PIPA126585

Supplier: Thermo Scientific PA126585

Description

Goat Polyclonal Antibody

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

PA1-26585 detects MCM7 from human samples. PA1-26585 is expected to cross react with mouse (78% conserved) due to sequence homology.PA1-26585 has been successfully used in Western blot procedures. Predicted molecular weight: 90 kDa. Positive control: HeLa cell lysate.The PA1-26585 immunogen is a synthetic peptide corresponding to a portion of human Minichromosome Maintenance Deficient 7 encoded in part by exons 8 and 9.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MCM7
Applications Western Blot
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unconjugated
Gene MCM7
Gene Accession No. P33993, Q61881
Gene Alias CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146
Gene Symbols MCM7
Host Species Goat
Immunogen Synthetic peptide corresponding to a portion of human Minichromosome Maintenance Deficient 7 encoded in part by exons 8 and 9.
Purification Method Antigen affinity chromatography
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4176
Target Species Human, Mouse
Content And Storage Store at 4°C, do not freeze
Product Type Antibody
Form Purified
Isotype IgG
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