MCP-1 Mouse anti-Human, Clone: 23007, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523712
In ELISAs, this antibody does not cross-react with recombit mouse (rm) CCL2, 3, 4, rhCCL3, 4, 5, 7, or 8. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
|PBS with 5% trehalose and No Preservative|
|C-C motif chemokine 2, HC11, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF, Monocyte chemotactic protein 1, MCP-1, Monocyte secretory protein JE, Small-inducible cytokine A2, CCL2, MCP1, SCYA2|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Neutralization, Western Blot|
|E. coli-derived recombit human CCL2/JE/MCP-1|
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