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MCP-1 Mouse anti-Human, Clone: 23007, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523712

Catalog No. PIMA523712


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Description

Description

In ELISAs, this antibody does not cross-react with recombit mouse (rm) CCL2, 3, 4, rhCCL3, 4, 5, 7, or 8. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Specifications

Specifications

MCP-1
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P13500
C-C motif chemokine 2, HC11, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF, Monocyte chemotactic protein 1, MCP-1, Monocyte secretory protein JE, Small-inducible cytokine A2, CCL2, MCP1, SCYA2
Mouse
IgG2b
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
6347
ELISA, Neutralization, Western Blot
23007
Unconjugated
CCL2
Lyophilized
CCL2
E. coli-derived recombit human CCL2/JE/MCP-1
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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