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MCP-1 Sheep anti-Human, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen PA175292

Catalog No. PIPA175292


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Description

Description

PA1-75292 specifically detects MCP1. PA1-75292 has been successfully used in ELISA applications. The PA1-75292 immunogen is Recombit MCP-1.

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Specifications

Specifications

MCP-1
Polyclonal
PBS with 0.09% sodium azide
P13500
Monocyte Chemotactic Protein 1, MCP-1
Sheep
IgG
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
6347
ELISA
Unconjugated
CCL2
Liquid
CCL2
Recombit human MCP-1
Affinity chromatography
RUO
Antibody
Polyclonal
Human
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