MD-1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141586
Suggested positive control: Ramos.Mammalian MD-1 is a homolog of Chicken MD-1, which was previously isolated as a v-myb-regulated gene, since its transcription increases rapidly after v-myb induction. MD-1 is associated at the cell surface with RP105. RP105 is a leucine-rich repaeat (LRR) molecule that is expressed on B-lymphocytes. It was first identified by a mAb that protects spleen B cells from irradiation-induced apoptosis (2). LRR proteins, such as Toll receptors, have a role in innate immunity. MD-1 does not have any homology to other molecules. MD-1 when expressed alone behaves as a secretory protein. Expression of MD-1 in a cell increases the expression of RP105.
|Synthetic peptide corresponding to residues 112-125 of human MD-1.|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.05% sodium azide|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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