MDMX, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528212
The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene.PA5-28212 targets MDMX in IF, IHC (P), and WB applications and shows reactivity with Human samples.The PA5-28212 immunogen is recombinant protein fragment corresponding to a region within amino acids 62 and 490 of Human MDMX.
|Recombinant protein fragment corresponding to a region within amino acids 62 and 490 of Human MDMX|
|Antigen affinity chromatography|
|Store at -20°C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|HDMX, MDMX, MRP1, MDM4-related protein 1, Mdm4, transformed 3T3 cell double minute 4, p53 binding protein, double minute 4, human homolog of, p53-binding protein, mdm2-like p53-binding protein, protein Mdm4, protein Mdmx|
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