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ABCB4 Mouse anti-Human, Clone: P3II-26, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA135605

Catalog No. 01-671-043


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Description

Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Specifications

Specifications

ABCB4
Monoclonal
Unconjugated
ABCB4
Liquid
ABCB4
MDR3.
1 mL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5244
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
P3II-26
tissue culture supernatant with 0.7% BSA and 0.1% sodium azide
P21439
ABC20, CD243, CLCS, GP170, MDR1, MGC163296, P-GP, PGY1
Mouse
IgG2b
RUO
Antibody
Monoclonal
Human
Documents
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