MEK5 Mouse anti-Human, Clone: 2C2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA519712
Peptide Sequence: MLWLALGPFP AMENQVLVIR IKIPNSGAVD WTVHSGPQLL FRDVLDVIGQ VLPEATTTAF EYEDEDGDRI TVRSDEEMKA MLSYYYSTVM EQQVNGQLIE PLQIFPRACK PPGERNIHGLThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
|PBS with no preservative; pH 7.4|
|Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5; MAPK/ERK kinase 5; MAP2K5; MEK5, MKK5, PRKMK5|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Immunocytochemistry, Immunofluorescence, Western Blot|
|MAP2K5 (AAH08838, 1 a.a. ∽ 120 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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