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MEK7 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527922

Catalog No. PIPA527922


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Description

Description

PA5-27922 targets MEK7 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27922 immunogen is recombit fragment corresponding to a region within amino acids 38 and 396 of Human MEK7. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.
Specifications

Specifications

MEK7
Polyclonal
Unconjugated
MAP2K7
Liquid
MAP2K7
Recombit fragment corresponding to a region within amino acids 38 and 396 of Human MEK7
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
O14733
Jnkk2, MAPKK7, MKK7, PRKMK7, SAPKK-4, SAPKK4, JNK-activating kinase 2, JNKK 2, MAP kinase kinase 7, MAPK/ERK kinase 7, MAPKK 7, MEK 7, SAPK kinase 4, c-Jun N-terminal kinase kinase 2, dual specificity mitogen-activated protein kinase kinase 7, stress-activated protein kinase kinase 4
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5609
Documents
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