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mGluR5 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA513361

Catalog No. PIPA513361


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Description

Description

GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.
Specifications

Specifications

mGluR5
Polyclonal
Unconjugated
GRM5
Liquid
GRM5
KLH conjugated synthetic peptide between 1020-1050 amino acids from the C-terminal region of human Metabotropic Glutamate Receptor 5 (GPRC1E)
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
2 mg/mL
PBS with 0.09% sodium azide
P41594, Q3UVX5
Metabotropic glutamate receptor 5 [Precursor]; mGluR5; GRM5; GPRC1E; MGLUR5
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
108071, 2915
Documents
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