Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

MilliporeSigma™ anti-methyl-PP2A, Clone: 2A10, ™ Non-distribution product as customer accommodation.

Manufacturer:  MilliporeSigma™ 041479/DEL

Catalog No. 50-171-269

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.
View substitute products »


Description

Description

Type 2 protein serine/threonine phosphatase (PP2A) is a trimer composed of a catalytic C subunit and two regulatory (A and B) subunits; many isoforms for the A and B subunits have been found. PP2A has a high specific activity against the subunit of phosphorylase kinase and is insensitive to Inhibitor-2. PP2A is distinguishable from PP2B/Calcineurin and PP2C by its partial activity in the absence of divalent cations, and by its high sensitivity to inhibition by okadaic acid. It is also thought to be the principal down-modulator of serine/threonine kinase cascades. PP2B requires Ca2+/calmodulin for activity, and is an activator of NFAT transcription factors. PP2C requires Mg2+, but is insensitive to okadaic acid, microcystin LR, or the calmodulin inhibitor trifluoperazine.

Western Blotting

Specifications

Specifications

methyl-PP2A
Unconjugated
Murine
150μg
Cell Signaling
Monoclonal
1mg/mL
Semi-purified
IgG1 κ
RUO
Primary
Chicken, Drosophila, Human, Murine, Porcine, Rabbit, Rat, Yeast
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit