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METTL7B Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520637

Catalog No. PIPA520637


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Description

Description

A suggested positive control is rat spleen tissue lysate. PA5-20637 can be used with blocking peptide PEP-0757.

MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
Specifications

Specifications

MettL7B
Polyclonal
Unconjugated
METTL7B
Liquid
METTL7B
A 16 amino acid peptide near the carboxy terminus of human MettL7B.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q6UX53, Q9DD20, Q562C4
UNQ594/PRO1180; methyltransferase-like protein 7B
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
196410, 366792, 71664
Documents
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