MFN2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527606
PA5-27606 targets MFN2 in WB applications and shows reactivity with Human samples. The PA5-27606 immunogen is recombit fragment corresponding to a region within amino acids 1 and 183 of Human MFN2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintece and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
|Recombit fragment corresponding to a region within amino acids 1 and 183 of Human MFN2|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|CMT2A, CMT2A2, CPRP1, HSG, MARF, hyperplasia suppressor, mitochondrial assembly regulatory factor, mitofusin-2, transmembrane GTPase MFN2|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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