Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

mGluR1 Rabbit anti-Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112753

Catalog No. 01-674-519


Add to cart

Description

Description

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. The Glutamate Receptor, Metabotropic, 1, (mGluR1 alpha) activates phospholipase C and participates in the central action of glutamate in the central nervous system, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.

This antibody is specific for the ~125k monomer or the ~250k mGluR1a dimer. Immunolabeling can be blocked by preadsorption of antibody with the antigenic peptide. A suggested positive control for this product is HEK-293 cell lysate.
Specifications

Specifications

mGluR1
Polyclonal
HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
P23385
mGluR1a, GPRC1A, GRM1A, Human metabotropic glutamate receptor 1 alpha mRNA complete cds
Rabbit
IgG
10 Miniblots
-20° C, Avoid Freeze/Thaw Cycles
Primary
24414
Immunohistochemistry (Frozen), Western Blot
Unconjugated
Grm1
Liquid
GRM1
Synthetic peptide corresponding to the C-terminal region of mGluR1a.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Rat
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit