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mGluR5 Mouse anti-Human, Clone: 464818, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524185

Catalog No. PIMA524185



Description

Description

In direct ELISAs and Western blots, no cross-reactivity with recombit human mGluR1, R2, R3, R4, R7, or R8 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.
Specifications

Specifications

mGluR5
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P41594
GRM5, GPRC1E, MGLUR5, Mglur5b, MGlu5
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
2915
Flow Cytometry, Western Blot
464818
Unconjugated
GRM5
Lyophilized
GRM5
Mouse myeloma cell line NS0-derived recombit human mGluR5 Gln21-Ser509
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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