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HLA-G Mouse anti-Human, APC, Clone: MEM-G/9, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119465

Catalog No. 01-676-200


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Description

Description

HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.

This antibody reacts with native form of human HLA-G1 on the cell surface as well as with soluble HLA-G5 isoform in its beta2-microglobulin associated form. Reactivity with HLA-G3 was also reported. It will not cross-react with mouse.
Specifications

Specifications

HLA-G
Monoclonal
0.1 mg/mL
PBS with 0.2% BSA and 15mM sodium azide
P17693
DADB-15K14.8, MHC-G
Mouse
IgG1
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
3135
Flow Cytometry
MEM-G/9
APC
HLA-G
Liquid
HLA-G
Recombit human HLA-G refolded with beta- 2 Microglobulin and peptide.
Purified
RUO
Antibody
Monoclonal
Human
Documents
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