HLA-G Mouse anti-Human, Biotin, Clone: MEM-G/1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA119512
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.This antibody reacts with denaturated HLA-G heavy chain.
|Recombit human HLA-G denaturated heavy chain.|
|PBS with 15mM sodium azide; pH 7.4|
|4° C, do not freeze|
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