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HLA-G Mouse anti-Human, Clone: MEM-G/2, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119394

Catalog No. 01-676-142


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Description

Description

This antibody recognizes the free heavy chain of all the HLA-G isoforms.

HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
Specifications

Specifications

HLA-G
Monoclonal
Unconjugated
HLA-G
Liquid
HLA-G
Bacterially expressed recombit HLA-G heavy chain (denatured)
Chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
MEM-G/2
PBS with 15mM sodium azide; pH 7.4
P17693
DADB-15K14.8, MHC-G
Mouse
IgG1
100 μg
4° C, do not freeze
Primary
3135
Documents
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