HLA-G Mouse anti-Human, Clone: MEM-G/2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA119394
This antibody recognizes the free heavy chain of all the HLA-G isoforms.HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
|Bacterially expressed recombit HLA-G heavy chain (denatured)|
|Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot|
|PBS with 15mM sodium azide; pH 7.4|
|4° C, do not freeze|
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