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HLA-DR1 Mouse anti-Human, Clone: MEM-267, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119393

Catalog No. 01-676-141


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Description

Description

HLA-DR1 belongs to the HLA class II beta chain paralogues. The MHC Class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. MHC Class II molecules are expressed in antigen presenting cells (APC). The beta chain is approximately 26-28 kDa. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation.
Specifications

Specifications

HLA-DR1
Monoclonal
1 mg/mL
PBS with 15mM sodium azide; pH 7.4
P04229
XXbac-BPG161M6.1, DRB1, DRw10, FLJ75017, FLJ76359, HLA-DR1B, HLA-DRB, HLA-DRB1*, SS1
Mouse
IgG2b
100 μg
4° C, do not freeze
Primary
3123
ELISA, Flow Cytometry, Western Blot
MEM-267
Unconjugated
HLA-DRB1
Liquid
HLA-DRB1
Purified, insoluble DR1 beta chain, expressed in E. coli inclusion bodies.
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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