Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

NDUFAF2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520831

Catalog No. PIPA520831


Add to cart

Description

Description

A suggested positive control is Raji cell lysate. PA5-20831 can be used with blocking peptide PEP-0945.

Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kappa-B-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.
Specifications

Specifications

NDUFAF2
Polyclonal
Unconjugated
NDUFAF2
Liquid
NDUFAF2
A 14 amino acid peptide from near the carboxy terminus of human Mimitin.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q8N183
B17.2L, MMTN, NDUFA12L, mimitin; Myc-induced mitochondrial protein; NDUFA12-like protein; mimitin, mitochondrial
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
91942
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit