MINA53 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520909
A suggested positive control is human heart tissue lysate. PA5-20909 can be used with blocking peptide PEP-1023.MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias.
|A 15 amino acid peptide near the amino terminus of human MINA.|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|MDIG, MINA53, NO52; MYC-induced nuclear antigen; mineral dust induced gene protein; mineral dust-induced gene protein; myc-induced nuclear antigen, 53 kDa; nucleolar protein 52|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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