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DUSP22 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA132648

Catalog No. PIPA132648

Item Discontinued This item has been discontinued by the supplier and is no longer available. Please reach out to your sales representative.


Description

Description

PA1-32648 detects MKPX from human samples. PA1-32648 has been successfully used in immunohistochemistry (paraffin tissue) applications. The PA1-32648 immunogen is: Synthetic peptide, KLH conjugated.

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

DUSP22
Polyclonal
Unconjugated
Q9NRW4
DUSP22
Synthetic peptide, KLH conjugated.
25 μg
Primary
Human
Antibody
IgG
Immunohistochemistry (Paraffin)
1 mg/mL
DUSP22
DKFZp586F2224, MKPX, PYST2
Rabbit
Antigen affinity chromatography
RUO
56940
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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