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MLF1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA525908

Catalog No. PIPA525908

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Specifications

Specifications

MLF1
Polyclonal
PBS with 0.09% sodium azide
P58340, Q9QWV4
myelodysplasia-myeloid leukemia factor 1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
17349, 4291
Flow Cytometry, Immunohistochemistry, Western Blot
Unconjugated
MLF1
Liquid
MLF1
KLH conjugated synthetic peptide between 215-244 amino acids from the C-terminal region of human MLF1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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