MMP3 Mouse anti-Human, Clone: SL-1 IID4, Invitrogen

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MS810PABX

Catalog No. PIMS810PABX

Description

MS810PABX targets MMP-3 in AP, IF, and WB applications and shows reactivity with Human samples. The MS810PABX immunogen is aPMA (4-aminophenylmercuric acetate) activated human MMP-3. MS810PABX detects MMP-3 which has a predicted molecular weight of approximately 43 kDa.

MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.

Specifications

• Antigen: MMP3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: MMP3
• Gene Alias: matrix metalloproteinase 3 (stromelysin 1, progelatinase); matrix metalloproteinase-3; proteoglycanase; stromelysin-1; transin-1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4314
• Content And Storage: -20°C
• Form: Liquid

• Applications: Affinity Purification, Immunofluorescence, Immunohistochemistry, Western Blot
• Clone: SL-1 IID4
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P08254
• Gene Symbols: MMP3
• Immunogen: APMA (4-aminophenylmercuric acetate) activated human MMP-3
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b