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MMP13, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA125218

Catalog No. PIPA125218

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

PA1-25218 detects MMP-13 from human samples.PA1-25218 has been successfully used in Western blot procedures.The PA1-25218 immunogen is a synthetic peptide corresponding to the propeptide region of human MMP-13.
Specifications

Specifications

MMP13
Polyclonal
Unconjugated
MMP13
Purified
MMP13
Synthetic peptide corresponding to the propeptide region of human MMP-13.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4
P45452
CLG3, MANDP1
Rabbit
IgG
25μg
Avoid Freeze/Thaw Cycles
Primary
4322
Documents
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