MMP13 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA513182
DescriptionMMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.
|KLH conjugated synthetic peptide between 295-324 amino acids from the C-terminal region of human MMP13|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.09% sodium azide|
|Collagenase 3; Matrix metalloproteinase-13; MMP-13; MMP13|
|-20° C, Avoid Freeze/Thaw Cycles|
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