Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

MMP14 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA125221

Catalog No. PA125221


Add to cart

Description

Description

PA1-25221 detects MMP-14 from human samples. PA1-25221 has been successfully used in ELISA, immunohistochemistry (paraffin) and Western blot procedures. The PA1-25221 immunogen is a synthetic peptide corresponding to the N-terminal domain of human MMP-14.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP ft.s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
Specifications

Specifications

MMP14
Polyclonal
Unconjugated
MMP14
Liquid
MMP14
Synthetic peptide corresponding to the N-terminal domain of human MMP-14.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
ELISA, Immunohistochemistry (Paraffin), Western Blot
0.25 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P50281
MMP-X1, MT1-MMP, MTMMP1
Rabbit
IgG
50 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
4323
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit