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MMP14 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA513183

Catalog No. PIPA513183


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Description

Description

This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.
Specifications

Specifications

MMP14
Polyclonal
PBS with 0.09% sodium azide
P50281, P53690
Matrix metalloproteinase-14 [Precursor]; MMP-14; EC 3.4.24.80; Membrane-type matrix metalloproteinase 1; MT-MMP 1; MTMMP1; Membrane-type-1 matrix metalloproteinase; MT1-MMP; MT1MMP; MMP-X1; MMP14
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
17387, 4323
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
MMP14
Liquid
MMP14
KLH conjugated synthetic peptide between 145-174 amino acids from the N-terminal region of human MMP14
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human, Mouse
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