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MMP16 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA129182

Catalog No. PIPA129182

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

PA1-29182 detects MMP16 from rat, mouse, human samples. PA1-29182 has been successfully used in immunohistochemistry (paraffin tissue) applications. The PA1-29182 immunogen is: Synthetic peptide corresponding to the catalytic domain of human MMP-16 / MT3-MMP.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP ft.s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene produces at least two transcripts, one which encodes a membrane-bound form and another a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.
Specifications

Specifications

MMP16
Polyclonal
Unconjugated
MMP16
Liquid
MMP16
Synthetic peptide corresponding to the catalytic domain of human MMP-16 / MT3-MMP.
Protein A
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry (Paraffin)
1 mg/mL
PBS with 0.2% BSA and 0.1% sodium azide; pH 7.4
P51512, Q9WTR0, O35548
C8orf57, DKFZp761D112, MMP-X2, MT-MMP2, MT-MMP3, MT3-MMP
Rabbit
IgG
500 μL
4° C, do not freeze
Primary
17389, 4325, 65205
Documents
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